Arnst, Kinsie : rechercher sur Z-Library

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1

Polymer conjugate of a microtubule destabilizer inhibits lung metastatic melanoma

Yang, Ruinan, Mondal, Goutam, Ness, Rachel A., Arnst, Kinsie, Mundra, Vaibhav, Miller, Duane D., Li, Wei, Mahato, Ram I.

Journal:

Journal of Controlled Release

Année:

2017

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2017

2

A potent, metabolically stable tubulin inhibitor targets the colchicine binding site and overcomes taxane resistance

Arnst, Kinsie E., Wang, Yuxi, Hwang, Dong-Jin, Xue, Yi, Costello, Terry, Hamilton, David, Chen, Qiang, Yang, Jinliang, Park, Frank, Dalton, James T, Miller, Duane D., Li, Wei

Journal:

Cancer Research

Année:

2017

Langue:

english

Fichier:

PDF, 4.78 MB

english, 2017

3

Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Anti-Tumor Efficacy

Banerjee, Souvik, Arnst, Kinsie E., Wang, Yuxi, Kumar, Gyanendra, Deng, Shanshan, Yang, Lei, Li, Guo-Bo, Yang, Jinliang, White, Stephen W., Li, Wei, Miller, Duane D

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2018

4

Synthesis and biological evaluation of indole-based UC-112 analogs as potent and selective survivin inhibitors

Wang, Qinghui, Arnst, Kinsie E., Xue, Yi, Lei, Zi-Ning, Ma, Dejian, Chen, Zhe-Sheng, Miller, Duane D., Li, Wei

Journal:

European Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2018

5

Tubulin Inhibitor-Based Antibody-Drug Conjugates for Cancer Therapy

Chen, Hao, Lin, Zongtao, Arnst, Kinsie, Miller, Duane, Li, Wei

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 5.37 MB

english, 2017

6

Structural modification of the 3,4,5-trimethoxyphenyl moiety in the tubulin inhibitor VERU-111 leads to improved antiproliferative activities

Wang, Qinghui, Arnst, Kinsie, Wang, Yuxi, Kumar, Gyanendra, Ma, Dejian, Chen, Hao, Wu, Zhongzhi, Yang, Jinliang, White, Stephen W., Miller, Duane D, Li, Wei

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2018

7

Current advances of tubulin inhibitors as dual acting small molecules for cancer therapy

Arnst, Kinsie E, Banerjee, Souvik, Chen, Hao, Deng, Shanshan, Hwang, Dong-Jin, Li, Wei, Miller, Duane D

Journal:

Medicinal Research Reviews

Année:

2019

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2019

8

Colchicine binding site agent DJ95 overcomes drug resistance and exhibits antitumor efficacy

Arnst, Kinsie E, Wang, Yuxi, Lei, Zi-Ning, Hwang, Dong-Jin, Kumar, Gyanendra, Ma, Dejian, Parke, Deanna N, Chen, Qiang, Yang, Jinliang, White, Stephen W, Seagroves, Tiffany N, Chen, Zhe-Sheng, Miller,

Journal:

Molecular Pharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 2.74 MB

english, 2019

9

Structure guided design, synthesis, and biological evaluation of 2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) analogs targeting the colchicine binding site in tubulin

Wang, Qinghui, Arnst, Kinsie, Wang, Yuxi, Kumar, Gyanendra K, Ma, Dejian, White, Stephen W., Miller, Duane D, Li, Weimin, Li, Wei

Journal:

Journal of Medicinal Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2019

10

Structure guided design, synthesis, and biological evaluation of 2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) analogs targeting the colchicine binding site in tubulin

Wang, Qinghui, Arnst, Kinsie, Wang, Yuxi, Kumar, Gyanendra K, Ma, Dejian, White, Stephen W., Miller, Duane D, Li, Weimin, Li, Wei

Journal:

Journal of Medicinal Chemistry

Année:

2019

Fichier:

PDF, 1.68 MB

2019

11

Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design

Wang, Tao, Wu, Chengyong, Wang, Chengdi, Zhang, Guiping, Arnst, Kinsie E., Yao, Yijun, Zhang, Zhixiong, Wang, Yuxi, Pu, Dan, Li, Weimin

Journal:

Biochemical and Biophysical Research Communications

Année:

2020

Langue:

english

Fichier:

PDF, 3.02 MB

english, 2020